Field of application
The Promass U 500 is a specialized single-use flowmeter designed for biopharmaceutical processes in the life sciences sector. It addresses the industry’s transition from reusable to disposable equipment and from batch to continuous production. Featuring multivariable measurement capabilities, this device delivers superior precision, dependable performance, and adherence to cGMP standards. Its design makes it particularly effective for upstream and downstream operations in monoclonal antibody (mAb) production.
The system consists of a disposable sensor available in four line sizes and a fixed base unit compatible with all variants. Heartbeat Technology automatically detects the flow range and confirms calibration integrity post-installation, streamlining setup and removing the requirement for on-site calibration. The transmitter includes a built-in web server, WLAN connectivity, and up to four I/O channels for simplified control and enhanced process monitoring.
Benefits
-
Industry-leading measurement precision – Utilizes Coriolis technology with multivariable measurement
-
Exceptional turndown ratio – Single sensor accommodates all disposable line sizes
-
Full cGMP compliance – Developed following current regulations with complete documentation
-
Quick and easy installation – One-hand mounting with automatic calibration transfer
-
Self-draining or air bubble removal – Enabled by multiple mounting orientations
-
Eliminates field calibration – Automatic verification through Heartbeat Technology
-
Advanced digital connectivity – Supports modern single pair Ethernet protocols
